Abstract: Objective：To investigate the incidence of gestational diabetes mellitus （GDM） in mobile population in Shenzhen, and to analyze those factors related to glucose metabolism. Methods：From January 2012 to June 2013, there were 850 pregnant women receiving prenatal check-up in our Department of obstetrics. The oral 75 g glucose tolerance test （OGTT） was conducted. Results：The incidence of GDM diagnosed by OGTT was 9.65% in Shenzhen area. Those pregnant women with risk factors, such as ageing over 35 years, abnormal labor history, repeated positive glycosuria, body weight＞75 kg before pregnancy, BMI≥25 kg/m2, macrosomia, positive HBsAg, three or more times of pregnancy, had higher rate of positive OGTT （P＜0.01）. Conclusions：All pregnant women should be asked OGTT test. The new diagnostic criteria of GDM is great benefit to diagnosis of GDM. Those pregnant women with high risk factors should be carefully follow-up visited.

Key words: Diabetes, gestational, Guangdong, Residential mobility, Risk factors