Abstract: Objective：To evaluate the application of natural-cycle in vitro fertilization-embryo transfer （IVF-ET） in infertile women with ovarian low response. Methods：The retrospective analysis was designed. The natural-cycle IVF-ET was applied in 80 infertile women with ovarian low response in Reproductive Medicine Center，Tianjin Central Hospital for Obstetrics and Gynecology, from January 2010 to June 2011. Patients were divided into two groups according to obtaining oocytes or not. Results：102 oocytes-retrieved cycles were performed in 80 cases. The obtained oocytes rate, embryo transfer rate and pregnancy rate in oocytes-retrieved cycles，the pregnancy rate in the obtained-oocytes cycles and clinical pregnancy rate in embryos transferred cycles were 77.2%，56.4%，16.8%，21.8% and 29.8%，respectively. LH values on the day of hCG administration in the obtained oocytes group was significantly higher than that in another group（P<0.05）. Conclusions：Natural-cycle IVF-ET is a simple，effective and economic therapeutics for patients with ovarian low response. LH values on the day of hCG administration may have a predicting value for obtaining oocytes.

Key words: Ovarian failure, premature, Fertilization in vitro, Embryo transfer, Menstrual cycle, Ovulation detection