Abstract: Heterotopic pregnancy refers to the coexistence of intrauterine and ectopic pregnancies. The incidence of this rare disease significantly increased with application of assistant reproductive technology. The ectopic pregnancies usually occur in the fallopian tube, cervix, ovary, abdomen and previous cesarean scar. Because of the atypical clinical manifestations and the interference of intrauterine pregnancy, many cases could be missed diagnosis, misdiagnosed and delayed treatment, which always leads to serious complications. The treatment options for heterotopic pregnancy include expectant treatment, fetal reduction, surgery, and so on. The treatment should be individualized, based on patient′s preference, ectopic pregnancy site, clinical symptoms and signs. At the same time, it is still the treatment challenges how to avoid the impact of the treatment procedure of ectopic pregnancy on intrauterine pregnancy, for those patients who want to keep their intrauterine pregnancies.

Key words: Pregnancy, ectopic, Pregnancy, Pregnancy, tubal, Cicatrix, Cesarean section