Abstract: The effects of myomas position, size and number on pregnancy, the operational indications of infertility complicated with uterine myomas, the effects of different operation ways on the pregnancy outcomes, and the optimal time of conceive after myomectomy were reviewed in this paper. The influence on fertility is in a decreasing order among submucosal, intramural and subserosal myomas, which means that the influence of submucosal myomas on fertility is greatest, and that the submucosal myomas with clinical symptoms should be removed while the subserosal myomas should not be recommended for operation. Operation treatment for the unexplained infertility should be based on the comprehensive evaluation on multiple factors and the strategy of individual-based treatment. Some new methods, such as the high-intensity focused ultrasound and the uterine-artery embolization, don′t fit for those women with pregnancy planning. Contraceptive time after operation should be adopted accordingly. It should be paid attention to the recurrence of myomas and the uterine rupture during pregnancy or labor after myomectomy.

Key words: Uterine neoplasms, Myoma, Infertility, female, Gynecologic surgical procedures, Pregnancy