Abstract: Birth defects prevention was one of important components to improve the population quality. Causes of birth defects were more complex， both genetic factors and environmental factors. So， birth defects prevention should be carried out from the social， medical， environmental， behavioral and other aspects. The current prevalence of birth defects， the challenges of birth defects intervention， and the successful practice of birth defects prevention by population and family planning network were reviewed in this paper.

Key words: Congenital abnormalities, Prevention, Family planning services