国际生殖健康/计划生育 ›› 2021, Vol. 40 ›› Issue (2): 157-162.doi: 10.12280/gjszjk.20200274

• 综述 • 上一篇    下一篇

薄型子宫内膜的治疗进展

刘奕彤(), 周抒   

  1. 116044 大连医科大学(刘奕彤);大连医科大学附属第一医院妇产科(周抒)
  • 收稿日期:2020-05-19 出版日期:2021-03-15 发布日期:2021-03-24
  • 通讯作者: 刘奕彤 E-mail:18741656178@163.com

Progress in the Treatment of Thin Endometrium

LIU Yi-tong(), ZHOU Shu   

  1. Dalian Medical University, Dalian 116044, Liaoning Province, China (LIU Yi-tong); Department of Obstetrics and Gynecology, The First Affiliated Hospital of Dalian Medical University, Dalian 116011, Liaoning Province, China (ZHOU Shu)
  • Received:2020-05-19 Published:2021-03-15 Online:2021-03-24
  • Contact: LIU Yi-tong E-mail:18741656178@163.com

摘要:

根据薄型子宫内膜的病理病因及其发病机制,通过大量的临床数据、病例报道及相关参考文献,总结了目前临床上较为常用的治疗方法,简单分析了其治疗原理、临床疗效及相关不良反应。基于目前国内外的研究进展,本文探讨了再生医学应用于促进子宫内膜生长的可能性,重点讨论了骨髓间质干细胞(BMSCs)和子宫内膜干细胞(EDSCs)的作用原理及临床可行性,同时指出了其有待克服的局限性。分析薄型子宫内膜的研究进展,旨在为未来的临床治疗及科研创新提供参考。

关键词: 子宫内膜, 生殖技术,辅助, 雌激素类, 间充质基质细胞, 富血小板血浆, 薄型子宫内膜

Abstract:

According to the pathological etiology of thin endometrium, this paper expounds the pathogenesis and the clinical treatment methods based on a large number of clinical data, case reports and relevant references. The brief principle, clinical efficacy and related side effects of treatment are also included. On the base of the current research progress and new diagnosis and treatment ideas, the possibility of regenerative medicine is filed a discussion. The functional principle and clinical feasibility of bone marrow mesenchymal stem cells (BMSCs) and endometrial stem cells (EDSCs) are mainly discussed, including their clinical feasibility and the limitations, which show us a new hot of further study. This review provides useful reference for clinical treatment of thin endometrium in the future.

Key words: Endometrium, Reproductive techniques,assisted, Estrogens, Mesenchymal stromal cells, Platelet-rich plasma, Thin endometrium