卵巢类固醇细胞瘤的研究进展

doi:10.12280/gjszjk.20220453

摘要/Abstract

摘要：

卵巢类固醇细胞瘤（steroid cell tumor，SCT）是一种临床少见的发生于卵巢的肿瘤，且具有恶性潜能。其具体病因尚不清楚，患者临床表现多为男性化体征，伴有雄激素水平异常升高。影像学检查无特异性，术前诊断困难，临床上容易漏诊及误诊。确诊依靠组织病理及免疫组织化学结果，易与多囊卵巢综合征、妊娠黄体瘤、卵泡膜细胞瘤和畸胎瘤等疾病混淆。治疗应根据肿瘤的良恶性及是否保留生育功能等进行个体化治疗，尽量做到早发现、早诊断、早治疗，改善患者预后。综述卵巢SCT的研究进展，以期提高临床医生对该病的认识。

关键词: 卵巢肿瘤, 免疫组织化学, 诊断, 治疗

Abstract:

Ovarian steroid cell tumor (SCT) is a rare tumor of the ovary with malignant potential. The exact etiology of ovarian SCT is not known. Most of patients have the masculine signs with abnormally high androgen levels. The imaging examination is non-specific, making the preoperative diagnosis difficulty. The clinical diagnosis is easily missed and misdiagnosed. The definite diagnosis depends on histopathological findings and immunohistochemistry. However, the diagnosis is easily confused with polycystic ovary syndrome, luteal tumor of pregnancy, theca cell tumor and teratoma. The treatment should be individualized according to the benignity and malignancy of the tumor, and whether fertility is preserved or not. Early detection, diagnosis and treatment should be done as much as possible to improve the prognosis. This article reviews the research progress of ovarian SCT in order to improve clinicians′ understanding of the disease.

Key words: Ovarian neoplasms, Immunohistochemistry, Diagnosis, Therapy

王敏, 马帅, 李杰. 卵巢类固醇细胞瘤的研究进展[J]. 国际生殖健康/计划生育杂志, 2023, 42(4): 339-342.

WANG Min, MA Shuai, LI Jie. Research Progress of Ovarian Steroid Cell Tumor[J]. Journal of International Reproductive Health/Family Planning, 2023, 42(4): 339-342.

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