国际生殖健康/计划生育 ›› 2009, Vol. 28 ›› Issue (6): 368-370.

• 综述 • 上一篇    下一篇

水通道蛋白与子宫内膜异位症

徐科君;吴瑞瑾   

  1. 310006杭州,浙江大学医学院附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2009-11-15 发布日期:2009-11-15

Aquaporins and Endometriosis

XU Ke-jun;WU Rui-jin   

  1. Women’s Hospital, School of Medicine, Zhejiang University, Hangzhou 310006, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2009-11-15 Online:2009-11-15

摘要: 水通道蛋白家族(aquaporins, AQPs)是一组参与水分子转运的跨膜蛋白,与血管新生、肿瘤扩散等生理病理机制有关,其在子宫内膜发生病变时出现异常表达。血管新生在子宫内膜异位症(endometriosis, EMs)发生发展中起重要的作用。设想水通道蛋白家族可能与子宫内膜异位症的发生发展具有相关性。

关键词: 水通道蛋白, 子宫内膜异位症, 血管新生

Abstract: Aquaporins(AQPs) are a family of water-transporting membrane proteins, which involved in pathophysiology of angiogenesis, tumor proliferation and so on. Aquaporins changed their expression in abnormal human endometrium. Angiogenesis plays an important role in occurrence and development of endometriosis. We presumed that aquaporins may be have relationship with the occurrence and development of endometriosis.

Key words: Aquaporins, Endometriosis, Angiogenesis