国际生殖健康/计划生育 ›› 2013, Vol. 32 ›› Issue (3): 214-217.

• 综述 • 上一篇    下一篇

薄型子宫内膜治疗的研究进展

田 甜, 赵 静,李艳萍   

  1. 410008 长沙,中南大学湘雅医院生殖医学中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-05-15 发布日期:2013-05-15
  • 通讯作者: 李艳萍

Therapy of Thin Endometrium

TIAN Tian,ZHAO Jing,LI Yan-ping   

  1. Reproductive Medical Center,Xiangya Hospital of Central South University,Changsha 410008,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-05-15 Online:2013-05-15
  • Contact: LI Yan-ping

摘要: 随着辅助生殖技术(ART)的发展,薄型子宫内膜是临床医生面临的又一挑战。目前已基本达成共识,认为过薄的子宫内膜可影响子宫内膜容受性,其是ART中周期取消和胚胎种植失败的原因之一,造成了患者经济上和心理上的压力。目前关于薄型子宫内膜治疗的报道很多,但这些方案多为个案报道或小规模研究,疗效有待进一步证实。从促进内膜细胞再生、改善内膜血流、促进生长因子表达等方面进行分类总结,探讨其可能的作用机制,为今后临床治疗和探索新的方案提供思路。

关键词: 子宫内膜, 生殖技术, 辅助, 受精, 体外, 胚胎移植, 治疗

Abstract: With the development of assisted reproductive technology(ART),clinician faced another challenge, thin endometrium. The reached agreement is that thin endometrium may affect endometrial receptivity. Thin endometrium is one of the reasons of cycle cancellation and implantation failure in ART,which caused economic and psychologycal pressure on patients. At present,there are many reports on therapy of thin endometrium,but those therapy protocols were mainly based on case reports or small scale study. So, the effectiveness need to be further confirmed. Now,we classified therapy protocols of thin endometrium as: improving cell regeneration, improving blood flow of endometrium,enhancing expression of growth factors,and discussed potential mechanisms, so as to explore a better therapy in future.

Key words: Endometrium, Reproductive technology, assisted, Fertilization in vitro, Embryo transfer, Therapy