国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2014, Vol. 33 ›› Issue (4): 318-320.

• 综述 • 上一篇    下一篇

体外培养与胚胎移植的策略选择

高戈，张云山   

  1. 300100 天津市中心妇产科医院生殖医学中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2014-07-15 发布日期:2014-07-15
  • 通讯作者: 张云山

Strategies of in Vitro Culture and Embryo Transfer in Human Assisted Reproductive Technology

GAO Ge，ZHANG Yun-shan   

  1. Reproductive Medicine Center，Tianjin Central Hospital of Gynecology Obstetrics，Tianjin 300100，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-07-15 Online:2014-07-15
  • Contact: ZHANG Yun-shan

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摘要： 人类辅助生殖技术（ART）是目前解决不孕症最为有效的治疗方式之一。在ART治疗过程中，体外培养条件以及胚胎移植的策略是直接影响其临床活产率和单胎妊娠率的关键因素。体外培养条件主要包括温度、pH值、氧浓度、培养液的成分以及培养过程中不同阶段是否应该更换培养液等。胚胎移植的策略则包含胚胎移植数量的选择、卵裂期与囊胚期移植的选择以及优质囊胚指标的选择等。结合近期国外研究成果对体外培养条件以及胚胎移植的策略中仍然存在争议的一些问题进行了探讨和综述。

关键词: 生殖技术, 辅助, 胚胎培养技术, 胚胎移植, 囊胚

Abstract: Human assisted reproductive technology（ART） is one of the most effective therapies for human infertility. In vitro culture condition and the strategy of embryo transfer are important factors of ART outcomes such as the live birth rate and the singleton pregnancies rate. Those conditions of in vitro culture include temperature, pH, oxygen concentration, medium and sequential or continuous culture. The strategy of embryo transfer involves the elective single or double embryo transfer, transfer in cleavage or blastocyst stage, and the index for selecting the best blastocyst. Based on recent studies, this review discussed above controversial problems.

Key words: Reproductive techniques, assisted, Embryo culture techniques, Embryo transfer, Blastocyst