国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2016, Vol. 35 ›› Issue (2): 93-95.

• 专家论坛 •    下一篇

赠卵IVF-ET技术相关伦理问题的再思考

史潇，全松   

  1. 510515 广州，南方医科大学南方医院生殖医学中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2016-03-15 发布日期:2016-03-15
  • 通讯作者: 全松

Ethic Thinking of Oocyte Donation in IVF-ET Technology

SHI Xiao, QUAN Song   

  1. Center of Reproductive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2016-03-15 Online:2016-03-15
  • Contact: QUAN Song

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摘要： 赠卵体外受精-胚胎移植（IVF-ET）技术的发展为卵巢储备功能低下及卵巢功能衰竭的患者带来生育希望的同时也带来了许多新的伦理问题。解决和协调赠卵IVF-ET技术的发展与伦理原则之间的冲突是确保技术合理应用的前提。卵子供需失衡，赠卵者经济补偿额度设定，赠/受卵者条件，以及匿名双盲子代告知的制度是目前的热点伦理问题。针对上述问题系统的回顾文献，提出了相应的解决办法：增加配子捐赠途径同时发展卵子冷冻技术是目前解决卵子供需冲突的办法之一；赠卵补偿额度可根据地区发展水平以及卫生经济学研究结果决定；随着各中心妊娠率的提高可考虑适当放宽对捐赠者卵子个数的要求；赠卵IVF前对受卵者进行全面评估以保障受者和子代的利益；匿名双盲可于合适时机揭盲。

关键词: 卵母细胞移植, 受精, 体外, 胚胎移植, 伦理学, 医学

Abstract: The development of in vitro fertilization-embryo transfer （ＩＶＦ－ＥＴ） with oocyte donation technology brings new hope for infertility patients with ovarian failure, as well as some new ethic problems for the whole society. The conflicts between the development of new technology and ethical problems should be integrated in consideration, which is the precondition of the reasonable application of this new technology. The hot ethic issues at present include the supply-demand imbalance of oocyte, donor compensation, requirement for donor and recipient, anonymous and child informed. We reviewed the previous publications and proposed some suggestions for these problems: to match gradually the supply-demand imbalance by increasing donation and developing oocyte-frozen technology, to plan the compensation according to the economic development and health-economic study, to adjust properly the requirement for donor-oocytes since the pregnant rate was increasingly improved, to evaluate comprehensively the psychology and economic state of recipient before IVF, and to reconsider accordingly the anonymous and child-informed regulations.

Key words: Oocyte donation, Fertilization in vitro, Embryo transfer, Ethics, medical