国际生殖健康/计划生育杂志 ›› 2025, Vol. 44 ›› Issue (2): 121-124.doi: 10.12280/gjszjk.20240326

• 病例报告 • 上一篇    下一篇

辅助生殖术后并发门静脉及肠系膜上静脉血栓形成一例

杜静, 王猛彪, 常瑞亚, 张宗翠, 王玲()   

  1. 730050 兰州,中国人民解放军联勤保障部队第九四〇医院生殖医学中心(杜静,常瑞亚,张宗翠,王玲),消化内科(王猛彪);甘肃中医药大学第一临床医学院(杜静,常瑞亚,王玲)
  • 收稿日期:2024-07-09 出版日期:2025-03-15 发布日期:2025-03-10
  • 通讯作者: 王玲,E-mail:SZYXZX2020@163.com

A Case Report of Portal Vein and Superior Mesenteric Vein Thrombosis Subsequent to Assisted Reproductive Technology

DU Jing, WANG Meng-biao, CHANG Rui-ya, ZHANG Zong-cui, WANG Ling()   

  1. Reproductive Medicine Center(DU Jing, CHANG Rui-ya, ZHANG Zong-cui, WANG Ling), Department of Gastroenterology (WANG Meng-biao), The 940th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army Lanzhou 730050, China; The First Clinical College of Medicine, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China (DU Jing, CHANG Rui-ya, WANG Ling)
  • Received:2024-07-09 Published:2025-03-15 Online:2025-03-10
  • Contact: WANG Ling, E-mail: SZYXZX2020@163.com

摘要:

辅助生殖技术(assisted reproductive technology,ART)术后的血栓多发生在上肢静脉、颈内静脉等上腔静脉以上的血管内,其主要原因与ART术后卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)形成有关。报告1例冻融胚胎移植术(frozen-thawed embryo transfer,FET)后3周患者,无明显诱因出现剑突下持续性疼痛不适,经腹部彩色多普勒超声等相关检查后,考虑门静脉及肠系膜上静脉血栓形成。积极予以吸宫术终止妊娠及抗凝、抗血小板治疗后好转出院,持续抗凝治疗半年复查未见血栓存在。该患者无OHSS形成,且血栓形成部位少见,对该病例进行回顾性分析,旨在提高对ART术后并发深静脉血栓的认识。

关键词: 生殖技术, 辅助, 静脉血栓形成, 门静脉血栓, 肠系膜上静脉血栓, 病例报告

Abstract:

The postoperation thrombosis after assisted reproductive technology (ART) may typically occur in precava vein and antrorse vein such as upper extremities vein and internal jugular vein, which is related mainly to the ovarian hyperstimulation syndrome (OHSS) following ART. We reporte a rare case of thrombosis in the portal vein and superior mesenteric vein after 3 weeks of the frozen-thawed embryo transfer (FET). The patient presented with the persistent subxiphoid pain without any obvious precipitating factors. Diagnostic evaluations, including abdominal color Doppler ultrasound, indicated the portal vein and superior mesenteric vein thrombosis. The pregnancy was terminated through suction curettage, following with anticoagulation and antiplatelet therapy. The patient was discharged after clinical improvement, and continued antiplatelet therapy. On six-month follow-up, the patient did not showed any thrombus recurrence. The patient did not develop OHSS, and the thrombus location was atypical. This retrospective analysis enhances our understanding of the complications following ART, such as the deep vein thrombosis.

Key words: Reproductive techniques, assisted, Venous thrombosis, Portal vein thrombosis, Superior mesenteric vein thrombosis, Case reports