高强度聚焦超声治疗子宫肌瘤对女性生育力的影响

doi:10.12280/gjszjk.20250100

摘要/Abstract

摘要：

高强度聚焦超声（high intensity focused ultrasound，HIFU）可以将超声波投射到人体的目标组织，造成靶组织凝固性坏死，是一种无创的治疗手段。HIFU对有生育要求的子宫肌瘤患者具有良好的临床疗效，能够改善生理功能、缓解疼痛，同时缩短住院时间，降低医疗费用，且发生出血、感染的可能性较小。HIFU治疗子宫肌瘤对卵巢功能影响较小，能够改善子宫内膜容受性，降低盆腔粘连的发生率，在保护女性生育力方面具有治疗优势。HIFU治疗子宫肌瘤还能够缩短治疗后再次妊娠间隔时间。目前关于HIFU治疗子宫肌瘤对妊娠影响的相关研究质量和可靠性有待进一步提高。从HIFU治疗子宫肌瘤对卵巢功能、女性生殖道、妊娠等方面的影响综述HIFU治疗子宫肌瘤对女性生育力的影响。

关键词: 高强聚焦超声消融, 平滑肌瘤, 生育力, 治疗, 妊娠

Abstract:

High intensity focused ultrasound (HIFU), as a kind of non-invasive treatment, can project the ultrasound wave to the target tissues of the body, causing coagulative necrosis of the target tissues. HIFU has good clinical efficacy for patients with uterine fibroids who have fertility requirements. HIFU can improve the physiological function, relieve pain, and shorten the hospitalisation time and reduce medical costs. It can also reduce the likelihood of bleeding and infection. HIFU treatment for fibroids has less impact on ovarian function, improves endometrial tolerance, and reduces the incidence of pelvic adhesions, suggesting therapeutic advantages for protecting women's fertility. HIFU treatment for fibroids can shorten the interval between pregnancies after the treatment. The quality and reliability of studies on the effect of HIFU on pregnancy need to be further improved. In this paper, we review the effects of HIFU treatment of fibroids on ovarian function, the female reproductive tract, pregnancy, and fertility reservation.

Key words: High-intensity focused ultrasound ablation, Leiomyoma, Fertility, Therapy, Pregnancy

万子华, 王佳丽, 张世霞, 刘畅. 高强度聚焦超声治疗子宫肌瘤对女性生育力的影响[J]. 国际生殖健康/计划生育杂志, 2025, 44(4): 348-352.

WAN Zi-hua, WANG Jia-li, ZHANG Shi-xia, LIU Chang. Effect of High Intensity Focused Ultrasound on Female Fertility in the Treatment of Uterine Fibroids[J]. Journal of International Reproductive Health/Family Planning, 2025, 44(4): 348-352.

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