Journal of International Reproductive Health/Family Planning ›› 2021, Vol. 40 ›› Issue (5): 407-410.doi: 10.12280/gjszjk.20210039

• Review • Previous Articles     Next Articles

Application of Follicular Phase Long-Acting GnRH Agonist Long Protocol in IVF

LI Wen-shu, LIU Xue-mei()   

  1. Reproductive Medicine Center, Yantai Yuhuangding Hospital, Affiliated Hospital of Qingdao University, Yantai 264000, Shandong Province, China
  • Received:2021-01-20 Published:2021-09-15 Online:2021-09-29
  • Contact: LIU Xue-mei E-mail:xuemeiliu02@yeah.net

Abstract:

Gonadotropin-releasing hormone agonist (GnRHa) has been widely used in the pituitary downregulation of in vitro fertilization and embryo transfer (IVF-ET), in which a variety of the controlled ovarian stimulation protocols were derived. The follicular phase long-acting GnRH agonist long protocol has been gradually used in the patients with endometriosis, polycystic ovary syndrome and poor ovarian response, as well as some patients with normal ovarian reserve in recent years. This protocol has the advantages of higher embryo implantation rate and clinical pregnancy rate by improving endometrial receptivity and embryonic quality, when compared with other protocols.

Key words: Ovulation induction, Superovulation, Fertilization in vitro, Ovarian reserve, Gonadotropin-releasing hormone