A Successful Pregnancy after Embryo Transfer of Non-Pronuclcus Embryos in Patient with Postoperative Endometriosis

doi:10.12280/gjszjk.20210246

Abstract

Abstract:

This is a case report of successful pregnancy after the frozen embryo transfer of non-pronuclcus embryos, in which the patient with postoperative endometriosis underwent the treatment of assisted reproductive technology (ART). Six months ago, the patient had the comprehensive operation of the separation of fallopian tube adhesion, the fistulation of tubal fimbria and the debridement of endometriosis debridement. In October 2018, two non-pronuclcus embryos were obtained after the ultra-long protocol. Leuprorelin (3.75 mg) was used in January 2019 (for 3 cycles) to prepare endometrium for frozen-thawed embryo transfer (FET), under the informed consent. Eventually, the patient gave birth to a healthy baby girl. This case inspires the individualized consideration on the choice of assisted pregnancy scheme for patients with endometriosis, and the exploration on the advantages and disadvantages of clinical use of non-pronuclcus embryos in order to obtain satisfactory pregnancy outcomes.

Key words: Reproductive techniques,assisted, Leuprolide, Endometriosis, Adenomyosis, Non-pronuclcus embryos

LAN Yun-zhu, WANG Fang, HUANG Gui-ying, CHEN Shao-wei. A Successful Pregnancy after Embryo Transfer of Non-Pronuclcus Embryos in Patient with Postoperative Endometriosis[J]. Journal of International Reproductive Health/Family Planning, 2022, 41(1): 22-24.

Figures/Tables 8

References 12

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日期	E₂ （pmol/L）	P （nmol/L）	LH （U/L）	FSH （U/L）	CA125 （U/mL）
2018.10.20	89.89	2.28	2.53	9.32	399.55
2018.11.23	46.12	1.65	0.46	6.05	146.28
2018.12.21	73.75	2.47	-	-	57.52
2019.01.02	5 355.06	2.69	0.73	-	-

日期	E₂ （pmol/L）	P （nmol/L）	LH （U/L）	FSH （U/L）	CA125 （U/mL）
2018.10.20	89.89	2.28	2.53	9.32	399.55
2018.11.23	46.12	1.65	0.46	6.05	146.28
2018.12.21	73.75	2.47	-	-	57.52
2019.01.02	5 355.06	2.69	0.73	-	-

日期	B超情况
2018.10.20	左卵巢直径<10 mm卵泡3枚,右卵巢<10 mm卵泡5枚
2018.11.23	内膜显示不清,左卵巢38 mm×27 mm液性暗区?右卵巢2~3 mm卵泡5枚,25 mm×15 mm、16 mm×8 mm、34 mm×18 mm不均质强回声包块待排查
2018.12.21	内膜4 mm,左卵巢16 mm×12 mm液性暗区?4~5 mm卵泡3枚,2 mm卵泡1枚;右卵巢29 mm×30 mm不均质强回声包块?（考虑卵巢子宫内膜异位囊肿）,4~5 mm卵泡3枚,2~3 mm卵泡2枚
2019.01.02	内膜8.6 mm,>18 mm卵泡2枚,>16 mm卵泡1枚,>14 mm卵泡1枚,>12 mm卵泡1枚

日期	B超情况
2018.10.20	左卵巢直径<10 mm卵泡3枚,右卵巢<10 mm卵泡5枚
2018.11.23	内膜显示不清,左卵巢38 mm×27 mm液性暗区?右卵巢2~3 mm卵泡5枚,25 mm×15 mm、16 mm×8 mm、34 mm×18 mm不均质强回声包块待排查
2018.12.21	内膜4 mm,左卵巢16 mm×12 mm液性暗区?4~5 mm卵泡3枚,2 mm卵泡1枚;右卵巢29 mm×30 mm不均质强回声包块?（考虑卵巢子宫内膜异位囊肿）,4~5 mm卵泡3枚,2~3 mm卵泡2枚
2019.01.02	内膜8.6 mm,>18 mm卵泡2枚,>16 mm卵泡1枚,>14 mm卵泡1枚,>12 mm卵泡1枚

日期	E₂ （pmol/L）	P （nmol/L）	LH （U/L）	FSH （U/L）	CA125 （U/mL）
2019.01.14	135.60	2.16	6.14	0.20	332.17
2019.02.12	88.09	1.39	9.22	0.20	-
2019.03.13	91.68	1.24	-	-	53.46
2019.04.11	57.21	1.33	0.20	11.83	20.44
2019.05.13	3 120.48	2.31	-	-	-