Abstract: Environmental endocrine disruptors are defined as some pollutants resided in the direct environment of organisms， which disrupt the normal endocrine function. Of these compounds， environmental hormones and their analogs can affect organisms enormously. In this review， we discussｅd the direct adverse effects of environmental estrogens， including the damages on reproduction and development， neuroendocrine，immune system， carcinogenic and teratogenic effects. And we introduced the relationship between environmental hormones and development?-origin of adult diseases. Epigenetics always play a key role in the long periods adverse effects, transgenerational effects， of environmental estrogens.

Key words: Environmental estrogens, Adverse effects, Development-origin of adult diseases, Transgenerational effects, Epigenetics