Abstract: Objective： To observe the analgesia and side-effects of patient-controled epidural analgesia（PCEA） with different doses of pentazocine combined with ropivacaine after abdominal hysterectomy，so as to find appropriate analgesic dose of pentazocine. Methods： 120 patients selected ASA Ⅰ~Ⅱ having abdominal hysterectomy were randomly divided into 4 groups. Each group included 30 patients. P1 Group：pentazocine 90 mg； P2 Group：pentazocine 150 mg； P3 Group： pentazocine 180 mg； F group： fentanyl 0.4 mg. Above treatment in four groups were combined with 0.2% ropivacaine for epudiral analgesia. The VAS score，Ramsay sedation score， PCA pumps push the number of patients（D1） and the actual entry number（D2）， the ratio of nausea and vomitting，were recorded. Results： The VAS score of P1 group at each time point was higher than those of P2， P3 and F group（P＜0.05）. The VAS scores of P2 and P3 group at each time point were higher than that of F group（although P＞0.05）. The Ramsay sedation scores of P2 group at 4 h，8 h and 12 h after operation were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at each time point were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at 8 h，12 h and 24 h after operation were higher than that of P2 group（P＜0.05）. The D1/D2 ratios of P1 group at 8 h，12 h and 24 h after operation were higher than those of P2， P3 and F group（P＜0.05）. The ratio of nausea and vomiting of F group were higher than that of P2 and P3 group（P＜0.05）. Conclusions： 150 mg pentazocine combined with 0.2% ropivacaine for epudiral analgesia after abdominal hysterectomy is more effective， with lower incidence of adverse reactions， suggesting that it is relatively safe and effective technique for epidural analgesia.Objective： To observe the analgesia and side?鄄effects of patient?鄄controled epidural analgesia（PCEA） with different doses of pentazocine combined with ropivacaine after abdominal hysterectomy，so as to find appropriate analgesic dose of pentazocine. Methods： 120 patients selected ASA Ⅰ~Ⅱ having abdominal hysterectomy were randomly divided into 4 groups. Each group included 30 patients. P1 Group：pentazocine 90 mg； P2 Group：pentazocine 150 mg； P3 Group： pentazocine 180 mg； F group： fentanyl 0.4 mg. Above treatment in four groups were combined with 0.2% ropivacaine for epudiral analgesia. The VAS score，Ramsay sedation score， PCA pumps push the number of patients（D1） and the actual entry number（D2）， the ratio of nausea and vomitting，were recorded. Results： The VAS score of P1 group at each time point was higher than those of P2， P3 and F group（P＜0.05）. The VAS scores of P2 and P3 group at each time point were higher than that of F group（although P＞0.05）. The Ramsay sedation scores of P2 group at 4 h，8 h and 12 h after operation were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at each time point were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at 8 h，12 h and 24 h after operation were higher than that of P2 group（P＜0.05）. The D1/D2 ratios of P1 group at 8 h，12 h and 24 h after operation were higher than those of P2， P3 and F group（P＜0.05）. The ratio of nausea and vomiting of F group were higher than that of P2 and P3 group（P＜0.05）. Conclusions： 150 mg pentazocine combined with 0.2% ropivacaine for epudiral analgesia after abdominal hysterectomy is more effective， with lower incidence of adverse reactions， suggesting that it is relatively safe and effective technique for epidural analgesia.Objective： To observe the analgesia and side?鄄effects of patient?鄄controled epidural analgesia（PCEA） with different doses of pentazocine combined with ropivacaine after abdominal hysterectomy，so as to find appropriate analgesic dose of pentazocine. Methods： 120 patients selected ASA Ⅰ~Ⅱ having abdominal hysterectomy were randomly divided into 4 groups. Each group included 30 patients. P1 Group：pentazocine 90 mg； P2 Group：pentazocine 150 mg； P3 Group： pentazocine 180 mg； F group： fentanyl 0.4 mg. Above treatment in four groups were combined with 0.2% ropivacaine for epudiral analgesia. The VAS score，Ramsay sedation score， PCA pumps push the number of patients（D1） and the actual entry number（D2）， the ratio of nausea and vomitting，were recorded. Results： The VAS score of P1 group at each time point was higher than those of P2， P3 and F group（P＜0.05）. The VAS scores of P2 and P3 group at each time point were higher than that of F group（although P＞0.05）. The Ramsay sedation scores of P2 group at 4 h，8 h and 12 h after operation were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at each time point were higher than that of P1 group（P＜0.05）. The Ramsay sedation score of P3 and F group at 8 h，12 h and 24 h after operation were higher than that of P2 group（P＜0.05）. The D1/D2 ratios of P1 group at 8 h，12 h and 24 h after operation were higher than those of P2， P3 and F group（P＜0.05）. The ratio of nausea and vomiting of F group were higher than that of P2 and P3 group（P＜0.05）. Conclusions： 150 mg pentazocine combined with 0.2% ropivacaine for epudiral analgesia after abdominal hysterectomy is more effective， with lower incidence of adverse reactions， suggesting that it is relatively safe and effective technique for epidural analgesia.

Key words: nalgesia, epidural, Analgesia, patient-controlled, Hysterectomy, Pentazocine, Fentanyl, Amides