Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism

Journal of International Reproductive Health/Family Planning ›› 2011, Vol. 30 ›› Issue (6): 454-457.

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Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism

XIU Rui-jie,GU Xiang-ying

ＴｉａｎｊｉｎＭｅｄｉｃａｌＵｎｉｖｅｒｓｉｔｙ General Hospital，Ｔｉａｎjｉｎ３０００52，Ｃｈｉｎａ

Received:1900-01-01 Revised:1900-01-01 Published:2011-11-15 Online:2011-11-15
Contact: GU Xiang-ying

Abstract

Abstract: Intrauterine device（IUD） is the most widely used contraceptive method in fertile woman in China. The main side effects of IUD are hypermenorrhea and bit bleeding in menstrual interphase. Indomethacin-releasing IUD is a efficient contraceptive， efficaciously preventing those side effects. A lot of study suggested that indomethacin inhibited ovulation in mammals. It is necessary to study the effects of inclomthacin-releasing IUD and its new mechanism to clarify whether indomethacin-releasing IUD inhibit ovulation and fertilization in the human famale.

Key words: ntrauterine devices, medicated, Indomethacin, Contraception, Molecular mechanisms of pharmacological action, Menorrhagia

XIU Rui-jie;GU Xiang-ying. Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism[J]. Journal of International Reproductive Health/Family Planning, 2011, 30(6): 454-457.

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Effect of Indomethacin Contained in the Indomethacin-releasing Intrauterine Device and Its Mechanism

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