|
|
Clinical Study of Etomidate During Induction of General Anesthesia on Laparoscopic Operation of Gynecology
LU Dong-dong;YUAN-Feng
2011, 30 (6):
444-445.
Objective： To compare the effects of etomidate and propofol on circulatory system during induction of general anesthesia on laparoscopic operation of gynecology. Methods： Sixty patients of laparoscopic operation of gynecology, at Ⅰ～Ⅱselected by ASA， ｗere randomly and equally divided into two groups. Etomidate group（E group） were treated with midazolam 0.05 mg/kg, fentanyl 2~3 μg/kg, etomidate 0.2 mg/kg, cis?鄄atracurium 0.15 mg/kg; propofol group（P group） with midazolam 0.05 mg/kg, fentanyl 2~3 μg/kg and propofol 1 mg/kg, cis-atracurium 0.15 mg/kg. Drugs were transfused by intravenous injection. Heart rate （HR）， systolic blood pressure（SBP） and diastolic blood pressure（DBP） were recorded before induction （T0）, after induction（T1）, intubation（T2） and after intubation 1（T3）， 3（T4）， 5（T5） min. The concentration of plasma norepinephrine（NE） was analysed on T0， Ｔ４，Ｔ5. Results：①The differences of HR， SBP and DBP on T0 between two groups were not statistically significant（P＞0.05）, while the differences of three parameters on T1 of the P group were statistically significant when respectively compared with those on T0 （P＜0.05）. ②HR，SBP and DBP of the two groups on T2 were significantly higher than those on T1（P＜0.05）, meanwhile three parameters on T2 ， T3 were significantly higher than those on T4（P＜0.05）.③NE level of E group on T4 and T5 were significantly higher than those of P group（P＜0.05）. Conclusions： Etomidate in patients as inducing general anesthesia for laparoscopic operation of gynecology has more stable hemodynamics than propofol.
Related Articles |
Metrics
|
