Journal of International Reproductive Health/Family Planning ›› 2012, Vol. 31 ›› Issue (6): 458-461.

• 综述 • Previous Articles     Next Articles

Adjunctive Therapy for the Poor Ovarian Response

WU Hui-hui,WU Long-qi,SHAO Xiao-guang   

  1. Reproductive Medicine Center, Dalian Obstetric and Gynecology Hospital,Dalian 116027,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-11-15 Online:2012-11-15
  • Contact: SHAO Xiao-guang

Abstract: It is a big challenge to improve the outcome of in vitro fertilization-embryo transplantation(IVF-ET) of poor ovarian responders for reproductive physicians. With the development of assisted reproduction technology (ART),the knowledge of poor ovarian response was accumulated. However,the etiology was poorly understood. There is no consensus on the diagnosis. Moreover,there is much controversy on the treatment strategy of poor responders. This review provided the current evidence and opinion on adjunctive therapy for the poor ovarian responders. Adjunctive medicine included growth hormone,testosterone,dehydroisoandrosterone,luteinizing hormone,oral contraceptive pills and estradiol during the controlled ovarian hyperstimulation or the previous cycle with the same ovarian stimulation protocol,by which to improve the poor responders′ outcomes.