Abstract: With the development of assisted reproductive technology（ART），clinician faced another challenge, thin endometrium. The reached agreement is that thin endometrium may affect endometrial receptivity. Thin endometrium is one of the reasons of cycle cancellation and implantation failure in ART，which caused economic and psychologycal pressure on patients. At present，there are many reports on therapy of thin endometrium，but those therapy protocols were mainly based on case reports or small scale study. So, the effectiveness need to be further confirmed. Now，we classified therapy protocols of thin endometrium as: improving cell regeneration, improving blood flow of endometrium，enhancing expression of growth factors，and discussed potential mechanisms, so as to explore a better therapy in future.

Key words: Endometrium, Reproductive technology, assisted, Fertilization in vitro, Embryo transfer, Therapy