Abstract: Objective： To investigate the relationship between phthalic acid esters （PAEs） exposure and sponstaneous abortion. Methods：In this retrospective study，107 spontaneous abortion cases and 152 induced abortion cases of early pregnancy were included，from January 2009 to December 2012. All the patients enrolled were required to complete a survey questionnaire about PAEs exposure. Results：By statistical analysis of logistic regression，it was showed that the shorter after the house decoration （OR=0.88，95%CI：0.81-0.96，P=0.00），the less office ventilation in summer （OR=0.95，95%CI：0.90-1.00，P=0.04） and the more utilization of preservative film（OR=1.14，95%CI：1.00-1.29，P=0.047），the higher relative risk of spontaneous abortion. In contrast，it was also observed that the more frequent of housecleaning （OR=3.50，95%CI：1.60-7.64，P=0.00），the lower relative risk of spontaneous abortion. Conclusions：The environmental pollutant of PAEs may be one of risk-factors of spontaneous abortion.

Key words: Diethylhexyl phthalate, Abortion, spontaneous, Environmental exposure, Questionnaires, Phthalic acid esters