Abstract: With the improving equipment and laboratory technology，as well as the optimized protocols of controlled ovarian stimulation，the pregnancy rate of assisted reproductive techniques（ART） has significantly increased. Meanwhile，the security of ART is of a focus. Infertility itself may be the risk factor of adverse pregnancy outcomes of ART. The increased rates of gestational hypertension，gestational diabetes，placenta previa，cesarean section，premature birth，multiple pregnancy，low birth weight，congenital malformations，and some latent risks of neonatal long-term disease（abnormal growth and development，malignant tumors in children，gene imprinting abnormalities），in those ART pregnancies could be related to excess ovarian stimulation，manipulation and frozen-thawing of gamete and embryo，in vitro embryonic culture and micromanipulation. The pregnancy outcomes of ART and risk factors were reviewed.

Key words: Reproductive techniques, assisted, Pregnancy complications, Pregnancy outcome