Abstract: Objective: To analyse the clinical outcomes of the ovum donation cycles conducted with the vitrified oocytes, so as to provide the predictive information for the clinical application of this technique. Methods: The clinical outcomes of 216 ovum donation cycles, which conducted with the vitrified-thawed oocytes undergoing IVF-ET in our reproductive center from February 2006 to October 2014, were retrospective analyzed. The main outcome parameters were the survival rate of the freezen-thawed oocytes, the normal fertilization（2PN） rate of in vitro fertilization, the cumulative clinical pregnancy rate, the implantation rate and the cumulative live birth rate. Results: The survival rate of the freezen-thawed oocytes was 82.0%（899/1 097）. The normal fertilization （2PN） rate was 76.9%（691/899）. The rates of implantation, cumulative clinical pregnancy and live birth were 21.4%（84/393）, 33.3%（72/216） and 27.3%（59/216）, respectively. The oocyte-to-baby rate was 6.5%（71/1 097）. Conclusions: There is relatively good clinical outcomes of the freezen-thawed oocytes when applied in the ovum donation.

Key words: Oocytes, Cryopreservation, Fertilization in vitro, Embryo transfer, Pregnancy outcome