Abstract: Micropapillary serous borderline tumor (MPSC) is a very rare type of ovarian cancers. Although it does not show the destructive invasive growth, it is associated with other malignant behaviors of ovarian cancer. Compared with the serous lesions without micropapillary structure, ovarian MPSC has the high probability of bilateral tumor and surface involvement, and the high incidence of invasive intraperitoneal implantation, which is equivalent to the non-invasive low-grade serous carcinoma. Until now, there are no clear clinical norms or guidelines for the treatment of MPSC. There is some controversy to the effect of micropapillary structure on the prognosis of those patients with serous borderline ovarian tumor. Combined with a case of ovarian MPSC with noninvasive intraperitoneal implantation from our hospital, this article mainly discusses the treatment of MPSC in order to improve the clinicians′ understanding.

Key words: Micropapillary, Ovarian neoplasms, Cystadenocarcinoma, serous, Drug therapy, combination