Mindfulness-Based Interventions in Patients Undergoing In Vitro Fertilization-Embryo Transfer: A Scoping Review

doi:10.12280/gjszjk.20250020

Abstract

Abstract:

Objective: To explore the application of mindfulness-based interventions (MBIs) in the patients undergoing in vitro fertilization-embryo transfer (IVF-ET), with a scoping review. Methods: Following the Joanna Briggs Institute methodology for scoping reviews, we systematically searched PubMed, Web of Science, Embase, Cochrane Library, CINAHL, CNKI, WanFang Data, VIP and CBM databases. Two researchers independently performed literature screening and data extraction, followed by synthesis and analysis of included studies. Results: Twenty-two studies were included. The intervention modalities included mindfulness-based stress reduction (MBSR), mindfulness-based cognitive therapy (MBCT), mindfulness-based yoga, mindfulness-based childbirth and parenting (MBCP), and acceptance and commitment therapy (ACT). The delivery formats included in-person training, online training and hybrid approaches. Most interventions were administered weekly (1-2 h/session). Most studies have shown that mindfulness intervention can alleviate anxiety and depression, significantly reduce the symptoms such as hostility and interpersonal sensitivity, and effectively lower the sense of stigma and enhance the happiness index and marital satisfaction, while mindfulness intervention can improve the sleep quality and physical comfort, as well as the quality of life and marriage. Meanwhile, most of IVF-ET patients expressed their satisfaction and recognition of the mindfulness intervention course. Conclusions: Preliminary evidence supports the diversity, integrative potential, efficacy and feasibility of MBIs in IVF-ET patients. Future research should optimize the personalized intervention protocols, explore the web-based remote delivery strategies, and further validate the long-term effect across multidimensional outcomes including psychological well-bing, sleep quality, mindfulness levels, and quality of life in IVF-ET patients.

Key words: Mindfulness, Cognitive behavioral therapy, Fertilization in vitro, Embryo transfer, Infertility, female, Scoping review

CUI Yu-fei, JIA Dong-ling, WANG Li-yan, LI Fu-lan, LIU Hui-hui, ZHANG Li-hong, HU Rong, HU Jun-ping. Mindfulness-Based Interventions in Patients Undergoing In Vitro Fertilization-Embryo Transfer: A Scoping Review[J]. Journal of International Reproductive Health/Family Planning, 2025, 44(5): 371-376.

Figures/Tables 2

References 35

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纳入分析文献	发表时间	研究类型	样本量（例，试验组/ 对照组）	试验组干预方法			对照组干预方法	干预时长	结局指标
纳入分析文献	发表时间	研究类型	样本量（例，试验组/ 对照组）	内容要素	干预形式	干预方式	对照组干预方法	干预时长	结局指标
Sahraian等^[14]	2024年	RCT	29/28	②③	线下培训	a、f	常规治疗	8周	AB
Tavousi等^[15]	2024年	RCT	22/22	①③⑤	线下培训	a、e、f	常规治疗	8周	A
Pandya^[16]	2024年	RCT	78/78	③	线上培训	a、f、g、h	常规治疗	20周	A
梁兰兰^[17]	2023年	类实验研究	52/52	①③	线下培训	a、e、f、h	常规治疗	8周	A
陈秀云等^[18]	2023年	RCT	50/50	①②③④⑤	线下培训	a、e、f	常规治疗	4周	A
$\dot{I}$nam等^[19]	2023年	描述性研究	17	①②	线上培训	c	-	-	B
李雨宸^[20]	2022年	类实验研究	33/34	①②③⑥⑦	线上培训	a、c、e、f、g、h、i	常规治疗	4周	A
张倩等^[21]	2022年	类实验研究	52/52	①②③	混合培训	c、e	常规治疗	12 d	A
毛新敏等^[22]	2021年	RCT	42/42	①②	-	a、e	正念干预	8周	A
Kalhori等^[23]	2020年	RCT	45/45	①②③⑥	线下培训	a、b、d、e、f、g、h	常规治疗	4~6周	A
王丹萍等^[24]	2020年	RCT	43/43	②③	线下培训	a、g	常规治疗	1个月	A
Bai等^[25]	2019年	RCT	78/78	①②	线下培训	a、c、e、g	常规治疗	4周	A
徐晓晓等^[26]	2019年	类实验研究	90	①②⑤⑦	混合培训	a、b、c、e、g	-	6周	A
Mousavi等^[27]	2019年	类实验研究	15/15	-	线下培训	f	常规治疗	-	A
Kalhori等^[28]	2019年	RCT	45/45	①②③⑥	线下培训	a、b、d、e、f、g、h	常规治疗	4~6周	A
Li等^[29]	2019年	质性研究	38	①③⑤	线下培训	a、b、c、e、g、h、i	-	6周	C
莫静^[30]	2018年	RCT	77/76	②③④⑦	线下培训	a、f、g	常规治疗	7周	A
刘凯等^[31]	2017年	RCT	42/41	①②③④⑤	线下培训	a、b、c、f、g	常规治疗	-	A
吴彩萍^[32]	2017年	RCT	50/50	①②③④⑦	线下培训	a、e、f	常规治疗	6周	A
Li等^[33]	2016年	类实验研究	58/50	①③⑤	线下培训	a、b、c、e、g、h、i	常规治疗	6周	A
唐惠艳等^[34]	2016年	类实验研究	40/40	①②③④⑤⑦	线下培训	a、b、c、e、f、g、h	常规治疗	6周	A
Paiva等^[35]	2015年	混合研究	25	②③	线下培训	a、f、g、i	-	12周	AC

纳入分析文献	发表时间	研究类型	样本量（例，试验组/ 对照组）	试验组干预方法			对照组干预方法	干预时长	结局指标
纳入分析文献	发表时间	研究类型	样本量（例，试验组/ 对照组）	内容要素	干预形式	干预方式	对照组干预方法	干预时长	结局指标
Sahraian等^[14]	2024年	RCT	29/28	②③	线下培训	a、f	常规治疗	8周	AB
Tavousi等^[15]	2024年	RCT	22/22	①③⑤	线下培训	a、e、f	常规治疗	8周	A
Pandya^[16]	2024年	RCT	78/78	③	线上培训	a、f、g、h	常规治疗	20周	A
梁兰兰^[17]	2023年	类实验研究	52/52	①③	线下培训	a、e、f、h	常规治疗	8周	A
陈秀云等^[18]	2023年	RCT	50/50	①②③④⑤	线下培训	a、e、f	常规治疗	4周	A
$\dot{I}$nam等^[19]	2023年	描述性研究	17	①②	线上培训	c	-	-	B
李雨宸^[20]	2022年	类实验研究	33/34	①②③⑥⑦	线上培训	a、c、e、f、g、h、i	常规治疗	4周	A
张倩等^[21]	2022年	类实验研究	52/52	①②③	混合培训	c、e	常规治疗	12 d	A
毛新敏等^[22]	2021年	RCT	42/42	①②	-	a、e	正念干预	8周	A
Kalhori等^[23]	2020年	RCT	45/45	①②③⑥	线下培训	a、b、d、e、f、g、h	常规治疗	4~6周	A
王丹萍等^[24]	2020年	RCT	43/43	②③	线下培训	a、g	常规治疗	1个月	A
Bai等^[25]	2019年	RCT	78/78	①②	线下培训	a、c、e、g	常规治疗	4周	A
徐晓晓等^[26]	2019年	类实验研究	90	①②⑤⑦	混合培训	a、b、c、e、g	-	6周	A
Mousavi等^[27]	2019年	类实验研究	15/15	-	线下培训	f	常规治疗	-	A
Kalhori等^[28]	2019年	RCT	45/45	①②③⑥	线下培训	a、b、d、e、f、g、h	常规治疗	4~6周	A
Li等^[29]	2019年	质性研究	38	①③⑤	线下培训	a、b、c、e、g、h、i	-	6周	C
莫静^[30]	2018年	RCT	77/76	②③④⑦	线下培训	a、f、g	常规治疗	7周	A
刘凯等^[31]	2017年	RCT	42/41	①②③④⑤	线下培训	a、b、c、f、g	常规治疗	-	A
吴彩萍^[32]	2017年	RCT	50/50	①②③④⑦	线下培训	a、e、f	常规治疗	6周	A
Li等^[33]	2016年	类实验研究	58/50	①③⑤	线下培训	a、b、c、e、g、h、i	常规治疗	6周	A
唐惠艳等^[34]	2016年	类实验研究	40/40	①②③④⑤⑦	线下培训	a、b、c、e、f、g、h	常规治疗	6周	A
Paiva等^[35]	2015年	混合研究	25	②③	线下培训	a、f、g、i	-	12周	AC