Abstract: With the development of fertility-sparing surgery (FSS) for ovarian malignant tumors in recent years, the safety, long-term prognosis and fertility of FSS have also been paid more and more attention. FSS treatment for early epithelial ovarian cancer does not increase the recurrence rate and mortality. FSS can be performed for malignant germ cell tumors regardless of tumor staging. The pregnancy rate after FSS was different, most of the patients could be able to conceive naturally. However, a few patients after FSS may need the assisted reproductive technology (ART). It is a common concern of both doctors and patients whether ovulation induction can lead to the recurrence of ovarian tumors. The FSS for the ovarian cancer at early stage and the ovarian borderline tumor is safe and feasible, and the effect of adjuvant chemotherapy on ovarian function after operation is reversible. There is no evidence at present that the ovulation induction will increase the postoperative recurrence rate or cause other malignant tumor. We discussed the safety of ovulation induction in those patients after FSS in this review.

Key words: Ovarian neoplasms, Fertility infertility, female, Ovulation induction, Reproductive techniques, assisted