Journal of International Reproductive Health/Family Planning ›› 2019, Vol. 38 ›› Issue (6): 498-503.

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Progress on the Ovarian Cryopreservation and Transplantation

WANG Sheng-cun,LI Bi-chun   

  1. College of Animal Science and Technology,Yangzhou University,Yangzhou 225009,Jiangsu Province,China(WANG Sheng-cun,LI Bi-chun);The Laboratory Animal Center of Nantong University,NanTong 226001,Jiangsu Province,China(WANG Sheng-cun)
  • Received:2018-08-16 Revised:2019-07-29 Published:2019-11-15 Online:2019-11-15
  • Contact: WANG Sheng-cun,E-mail:wsc@ntu.edu.cn E-mail:wsc@ntu.edu.cn
  • Supported by:
     

Abstract: There are a large number of eggs in the ovaries of mammals, which is a resource pool of female germ cells. It is expected to restore maternal fertility, and to maintain normal levels of hormones, by the cryopreservation of healthy ovarian tissue, rapid resuscitation and then orthotopic transplantation to the pelvic cavity or heterotopic transplantation to the subcutaneous and renal capsule and other parts. The success of ovarian tissue transplantation depends on the size of graft, the duration of local ischemia, exogenous antioxidants and angiogenic factors. At present, there have been a few reports of human ovarian cryopreservation and transplantation, and the success of live births. More animal experiments confirmed this possibility. In this paper, the research progress on the ovarian cryopreservation and transplantation is reviewed.

Key words: Ovary, Freezing, Cryopreservation, Transplantation, Fertility, Review

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