Abstract: The main clinical manifestations of submucous uterine fibroid include abnormal menstruation and leukorrhagia. Giant submucous uterine fibroid may be accompanied by infection and necrosis due to gravity-caused prolapse outside the external cervical outlet. It may also be accompanied by compressive symptoms such as constipation, frequent and urgent urination and dysuria. The main treatment is open surgery. Here, a case of giant submucous uterine fibroid accompanied by infection, necrosis, severe anemia and dysuria is reported. The process of diagnosis and treatment, especially preoperative preparation, is summarised, so as to improve the understanding of this complex disease.

Key words: Leiomyoma, Uterine neoplasms, Mucous membrane, Necrosis, Infection, Anemia