Research Progress on the Relationship between Endometriosis and Intestinal Flora Imbalance

doi:10.12280/gjszjk.20220468

Abstract

Abstract:

Endometriosis (EMs) is a common hormone-dependent disease in gynecology, which is most common in women of reproductive age. Although EMs is a benign disease, it has the properties of adhesion, invasion, metastasis and other malignant tumors, and it is prone to repeated attacks. EMs seriously affects the daily life and physical and mental health of female patients. The specific pathogenesis of EMs is still unclear. Many studies have demonstrated that the imbalance of intestinal flora plays an important role in the pathogenesis of EMs. The impact of intestinal flora imbalance on the pathogenesis of EMs may be related to the mechanisms involved in immune regulation, lipopolysaccharide generation, inflammatory factors and angiopoietin release, and sex hormone metabolism. In this review, the intestinal flora imbalance and mechanism related to the pathogenesis of EMs were summarized.

Key words: Endometriosis, Gastrointestinal microbiome, Immunity, Diagnosis, Therapy

ZHANG Hai-xia, FENG Xiao-ling. Research Progress on the Relationship between Endometriosis and Intestinal Flora Imbalance[J]. Journal of International Reproductive Health/Family Planning, 2023, 42(1): 66-71.

References 43

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