Abstract: Ｗｉｔｈ ｔｈｅ ｅｖｅｒ－ｉｎｃｒｅａｓｉｎｇ ｐｏｐｕｌａｒｉｔｙ ａｎｄ ｄｅｖｅｌｏｐｍｅｎｔ ｏｆ ｃｒｙｏｐｒｅｓｅｒｖｅｄ ｅｍｂｒｙｏｓ ｔｅｃｈｎｉｑｕｅ，ａ ｌａｒｇｅ ｎｕｍｂｅｒ ｏｆ ｓｕｒｐｌｕｓ ｅｍｂｒｙｏｓ ｈａｖｅ ｂｅｅｎ ｇｅｎｅｒａｔｅｄ ｗｉｔｈ ｉｎｃｒｅａｓｉｎｇ ｐｅｒｃｅｎｔａｇｅ ｏｆ ａｃｃｕｍｕｌａｔｉｏｎ ｐｒｅｇｎａｎｃｙ． Hｕｎｄｒｅｄｓ ｏｆ ｔｈｏｕｓａｎｄｓ ｏｆ ｆｒｏｚｅｎ ｅｍｂｒｙｏｓ， patients， physicians and embryologists feel it difficult how to deal with. Ａ ｃｅｎｔｒａｌ ｃｈａｌｌｅｎｇｅ was to make ｄｅｃｉｓｉｏｎ of ｔｈｅ ｄｉｓｐｏｓｉｔｉｏｎ ｏｆ ｅｘｃｅｓｓ ｅｍｂｒｙｏｓ． Ｎｏｗ， ｓｏｍｅ ｃｏｕｎｔｒｉｅｓ ｈａｖｅ ｄｅｖｅｌｏｐｅｄ the ｌａｗｓ ｏｒ ｇｕｉｄｅｌｉｎｅｓ ｔｏ ｇｏｖｅｒｎ ｔｈｅ ｄｉｓｐｏｓｉｔｉｏｎ. Rational disposition was three methods， ｄｉｓｐｏｓａｌ， ｄｏｎａｔｉｏｎ ｔｏ ｍｅｄｉｃａｌ ｒｅｓｅａｒｃｈ， ｏｒ donation ｔｏ ａ ｒｅｃｉｐｉｅｎｔ ｉｎｆｅｒｔｉｌｅ ｃｏｕｐｌｅ ｆｏｒ ｉｎｆｅｒｔｉｌｉｔｙ ｔｒｅａｔｍｅｎｔ． Ｉｓｓｕｅｓ ｒｅｌａｔｅｄ ｔｏ ｔｈｅ ｓｕｒｐｌｕｓ ｅｍｂｒｙｏｓ ｍａｙ ｔｒｉｇｇｅｒ ａ ｓｅｒｉｅｓ ｏｆ ｅｔｈｉｃａｌ ａｎｄ ｌｅｇａｌ ｃｏｎｔｒｏｖｅｒｓｉｅｓ． Ｉｎ ｔｈｉｓ ｒｅｖｉｅｗ，ｈｏｗ ｔｏ ｕｎｄｅｒｓｔａｎｄ ａｎｄ ｔｒｅａｔ ｐｒｏｐｅｒｌｙ ｔｈｏｓｅ ｅｔｈｉｃａｌ ｉｓｓｕｅｓ ｗａｓ ｆｏｃｕｓｅｄ．

Key words: Fertilization in vitro, Embryo transfer, Freezing, Cryopreservation, Embryo disposition, Ethics, Surplus embryos