Abstract: Spermiogenesis is the terminal differentiation process during which the round spermatid develops into the tadpole-shaped spermatozoon undergoing morphological changes, including the condensation of spermatid nucleus, the formation of acrosome and tail, the elimination of residual body and the transient appearance of manchette. Recently, with the development and application of new bio-techniques such as gene knockout, gene expression as well as gene functional analysis, many spermiogenesis-related genes and proteins have been unveiled. Some of those proteins were proved to play crucial roles in spermiogenesis. Herein, we reviewed the research advances in spermiogenesis-related proteins, including Golgi apparatus proteins, flagellum-related proteins and residual body-related proteins.

Key words: Spermatozoa, Spermatogenesis, Proteins, Acrosome