Abstract: Polycystic ovary syndrome（PCOS） is the most common endocrine disorder in women. This syndrome often occurs in perimenarcheal girls. Some of the pathological features of adolescent PCOS are often similar to the physiological changes of puberty. It is important to make early diagnoses and early treatment for these patients，which is helpful to prevent the long term complications of adolescent PCOS.

Key words: Polycystic ovary syndrome, Puberty, Insulin resistance, Hyperandrogenism, Therapy