Abstract: Human life and health has been damaged by the growing air pollution. The epidemiologic studies showed that the serious atmospheric pollution had multiple negative impacts on reproductive system. For male，damage from pollution shows the reduced testis size and weight，the decreased sperm concentration and total sperm count，the lowered sperm motility，and even abnormal morphology of spermatozoa and aberration of chromatin structures and DNA fragmentation, which leads to dysfunction of reproductive system and male infertility. For female，air pollution are related to abnormal ovarian structure and function，dysplastic germ cell，the lowered ovulation rate and the disorder of estrogen secretion. Moreover，long-term exposure to air pollution can cause the increased abortion rate and fetal malformation. We reviewed the research advances in the effects of main air pollutants on male and female reproductive system，reproductive cells，reproductive function and embryo development.

Key words: Air pollutants, Genitalia, female, Genitalia, male, Germ cells, Embryonic development