Abstract: Decidualization involved in endometrial receptivity is the important step during process of pregnancy. The injury of decidualization is associated with the early pregnancy loss. The cytoskeleton reorganization of the endometrial stromal cells related to the decidualization depends on the changes of cytoskeleton members such as intermediate filament, microfilament, microtubule and so on. It also refers to the cytoskeletal dynamic change regulated by skeleton binding protein. In this review, we discussed the cytoskeleton changes during decidualization, hormonal effect on cytoskeleton of the decidualizing endometrial stromal cells, as well as the autoregulation of decidualization once the cytoskeleton changes.

Key words: Decidua, Cytoskeleton, Endometrium, Gonadal steroid hormones