国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2011, Vol. 30 ›› Issue (5): 371-374.

• 综述 • 上一篇    下一篇

多囊卵巢综合征对妊娠结局的影响

闫 雪 ,徐兴华, 陈子江   

  1. 250021 济南，山东大学附属省立医院生殖医学中心；国家辅助生殖与优生工程技术研究中心；生殖内分泌教育部重点实验室；山东省生殖医学重点实验室
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-09-15 发布日期:2011-09-15
  • 通讯作者: 陈子江

Impact of Polycystic Ovary Syndrome on Pregnancy Outcome YAN Xue

YAN Xue， XU Xing-hua， CHEN Zi-jiang   

  1. Center for Reproductive Medicine， Provincial Hospital Affiliated to Shandong University； National Research Center for Assisted Reproductive Technology and Reproductive Genetics；The Key Laboratory for Reproductive Endocrinology of Ministry of Education； Shandong Provincial Key Laboratory of Reproductive Medicine， Jinan 250021， China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-09-15 Online:2011-09-15
  • Contact: CHEN Zi-jiang

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摘要： 多囊卵巢综合征（PCOS）主要累及生育年龄妇女，可引起内分泌和代谢紊乱。其临床表现复杂多样，患者常伴有肥胖、外周组织胰岛素抵抗和胰岛素细胞功能缺陷，增加其糖耐量异常和患糖尿病的概率。此外，PCOS还常伴有血脂异常和高血压等代谢障碍。这些都可能增加PCOS患者的妊娠期并发症如妊娠期糖尿病及妊娠期高血压的风险。综述PCOS对妊娠期并发症及新生儿结局的影响。

关键词: 多囊卵巢综合征, 表型, 妊娠结局, 妊娠并发症, 婴儿, 新生, 肥胖症

Abstract: Polycystic ovary syndrome（PCOS） which mainly affect women of reproductive age can cause endocrine and metabolic disorders. Its clinical manifestations are multifarious and heterogeneous. obesity， peripheral insulin resistance and impaired beta cell function are common in patients with PCOS， which increase the incidence of glucose intolerance and diabetes. Moreover， PCOS often accompany with dyslipidemia and hypertension. All these amplify the risk of pregnancy complication such as gestational diabetes and pregnancy induced hypertension syndrome. This paper reviewed the impact of PCOS on pregnancy complication and newborn outcome.

Key words: Polycystic ovary syndrome, Phenotype, Pregnancy outcome, Pregnancy complications, Infant, newborn, Obesity