国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2015, Vol. 34 ›› Issue (1): 48-50.

• 论著 • 上一篇    下一篇

氯米芬供精人工授精周期妊娠率与人绒毛膜促性腺激素日卵泡大小的关系

刘宇，樊荣荣，宋革，钟小英，陈瑞玲，潘萍，姜荣华，李秋华，曾丽萍   

  1. 510600 广州，广东省计划生育专科医院（刘宇，宋革，钟小英，陈瑞玲，潘萍，姜荣华，李秋华，曾丽萍）；中山大学附属第一医院妇产科（樊荣荣）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-01-15 发布日期:2015-01-15
  • 通讯作者: 刘宇

Association between Pregnancy Rate of AID with Clomiphene Citrate and Follicle Size on hCG Day

LIU Yu，FAN Rong-rong，SONG Ge，ZHONG Xiao-ying，CHEN Rui-ling，PAN Ping，JIANG Rong-hua，LI Qiu-hua，ZENG Li-ping   

  1. Guangdong Provincial Family Planning Special Hospital，510600 Guangzhou，China（LIU Yu，SONG Ge，ZHONG Xiao-ying，CHEN Rui-ling，PAN Ping，JIANG Rong-hua，LI Qiu-hua，ZENG Li-ping）；Department of Gynecology，The First Affiliated Hospital，Sun Yat-Sen University，510080 Guangzhou，China（FAN Rong-rong）
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-01-15 Online:2015-01-15
  • Contact: LIU Yu

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摘要： 目的：探讨氯米芬诱导排卵的供精人工授精（AID）周期注射人绒毛膜促性腺激素（hCG）日卵泡直径与妊娠率的关系。方法：回顾性分析氯米芬诱导排卵行AID共212个周期，根据hCG日最大卵泡直径分为：A组（18～19.5 mm）、B组（20～21.5 mm）、C组（22～23.5 mm）、D组（≥24 mm），分析比较4组的周期妊娠率。结果：4组妊娠率分别为24.39%、14.29%、18.18%、7.14%，其差异无统计学意义（P＞0.05）。结论：就本研究目前的资料分析，氯米芬周期hCG扳机日卵泡直径与妊娠率无相关性。

关键词: 生殖技术, 辅助, 授精, 人工, 氯米芬, 卵泡, 妊娠率

Abstract: Objective：To investigate the association between follicle size on human chorionic gonadotropin (hCG) day and clinical pregnancy rate in cycles with clomiphene citrate. Methods：212 infertile couples who accepted artificial insemination with donor semen treatment cycles were evaluated retrospectively in this study. They were divided into four groups according to the diameter of leading follicle on the day of hCG ｉｎｊｅｃｔｉｏｎ： ｇｒｏｕｐ Ａ（１８-１９．５ ｍｍ）， ｇｒｏｕｐ Ｂ（２０-２１．５ ｍｍ）， ｇｒｏｕｐ Ｃ（２２-２３．５ ｍｍ） ａｎｄ ｇｒｏｕｐ Ｄ（ａｂｏｖｅ ２４ ｍｍ）． Ｔｈｅ ｐｒｅｇｎａｎｃｙ ｏｕｔｃｏｍｅｓ ｗｅｒｅ ｃｏｍｐａｒｅｄ． Ｒｅｓｕｌｔｓ：Ｔｈｅ ｐｒｅｇｎａｎｃｙ ｒａｔｅｓ ｏｆ ｆｏｕｒ ｇｒｏｕｐｓ ｗｅｒｅ ２４．３９％， １４．２９％， １８．１８％ ａｎｄ ７．１４％． Ｔｈｅｒｅ ｗａｓ ｎｏｔ ｓｉｇｎｉｆｉｃａｎｔ ｄｉｆｆｅｒｅｎｃｅ ａｍｏｎｇ ｔｈｅ ｆｏｕｒ ｇｒｏｕｐｓ（Ｐ＞０．０５）． Ｃonclusions：There is not association between pregnancy rate of AID in cycles with clomiphene citrate and follicle size on hCG day according to our present study.

Key words: Reproductive techniques, assisted, Insemination, artificial, Clomiphene, Ovarian follicle, Pregnancy rate