国际生殖健康/计划生育 ›› 2012, Vol. 31 ›› Issue (6): 449-451.

• 论著 • 上一篇    下一篇

多囊卵巢综合征致不孕50例临床分析

凌 静, 谭 洁, 戴 洁, 崔毓桂, 刘嘉茵   

  1. 214400 江苏江阴,东南大学附属江阴人民医院妇产科(凌 静,谭 洁,戴 洁);南京医科大学附属第一医院生殖医学科(崔毓桂,刘嘉茵)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-11-15 发布日期:2012-11-15

Clinical Analysis of PCOS Infertility of 50 Cases

LING Jing,TAN Jie,DAI Jie,CUI Yu-gui,LIU Jia-yin   

  1. Department of Obstetrics and Gynecology,Jiangyin People′s Hospital,Jiangyin 214400,Jiangsu Province,China(LING Jing,TAN Jie,DAI Jie);Department of Reproductive Medicine, the First Affiliated Hospital,Nanjing Medical University, Nanjing 210029,China(CUI Yu-gui,LIU Jia-yin)
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-11-15 Online:2012-11-15

摘要: 目的:回顾性分析不孕门诊多囊卵巢综合征(PCOS)患者的不孕因素,探讨对PCOS不孕的综合治疗方法。方法:选择2009年1月—2011年4月收治的PCOS患者50例为研究对象,分析PCOS致不孕的因素,并总结临床治疗的经验。结果:50例患者中,39例有卵泡发育成熟,占78.0%;妊娠30例,占60.0%;先兆流产5例,占16.7%;稽留流产5例,占16.7%;2例出现OHSS,占6.7%;双胎妊娠1例,占3.3%;异位妊娠2例,占6.7%。23例顺利分娩。结论:PCOS是发病多因性、临床表现呈多态性的内分泌综合征,病理机制涉及高雄激素血症、胰岛素抵抗及高胰岛素血症,因此,临床上应采取综合方法治疗PCOS导致的不孕症。

关键词: 多囊卵巢综合征, 不育, 女(雌)性, 无排卵, 综合疗法, 雄激素增多症, 胰岛素抗药性, 氯米芬

Abstract: Objective:To analyze retrospectively the infertile factors of patients with polycystic ovary syndrome (PCOS) and the pathological mechanism, and to discuss its comprehensive therapy. Methods:Clinical analysis of the pathological mechanism of infertility induced by PCOS in 50 PCOS patients was did from infertility clinic in our hospital from Jan-09 to Apr-11,including the comprehensive treatment. Results:In 50 cases, there were 39 cases with mature follicles(78.0%),30 cases of pregnant(60.0%),5 cases of threatened abortion(16.7%),5 cases of missed abortion(16.7%),2 cases of ovarian hyperstimulation syndrome(OHSS)(6.7%),1 case of twin pregnancy(3.3%),2 cases of ectopic pregnancy (6.7%),23 cases were labored successfully. Conclusions:PCOS is a endocrine disorder of multiple etiological factors and clinical manifestations including hyperandrogenism,insulin resistance and hyperproinsulinemia. So the treatment for PCOS infertility should be comprehensive.

Key words: Polycystic ovary syndrome