国际生殖健康/计划生育 ›› 2011, Vol. 30 ›› Issue (2): 146-149.

• 综述 • 上一篇    下一篇

天然萜类化合物在宫颈癌抗癌机制中的研究

张莉莉,张淑兰   

  1. 110004 沈阳,中国医科大学附属盛京医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-03-15 发布日期:2011-03-15
  • 通讯作者: 张淑兰

Research Progresses on the Anticancer Mechanisms of Natural Terpenes in Cervical Cancer

ZHANG Li-li, ZHANG Shu-lan   

  1. Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang 110004, China
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-03-15 Online:2011-03-15
  • Contact: ZHANG Shu-lan

摘要: 随着中草药低毒高效的特点逐渐为大家认知,越来越多的中草药被用于宫颈癌的治疗。萜类化合物是中草药中一类比较重要的化合物,现已发现青蒿素、香樟醇、冬凌草甲素和大豆皂苷等多种萜类化合物表现出抗宫颈癌活性,其中二萜化合物紫杉醇已广泛应用于宫颈癌治疗,并且取得了较好的临床疗效,该类化合物的抗癌机制也正处于研究中。就萜类物质在宫颈癌抗癌机制中的研究进行综述。

关键词: 萜类, 宫颈肿瘤, 癌, 药物疗法

Abstract: More and more Chinese herbal medicine is used for the therapy of cervical cancer, as its high?-efficiency and low-toxin advantages are gradually recognized. Terpenes is a class of important compounds in Chinese herbal medicine. Recently, a variety of terpenoids with anti?-tumor activity have been found, such as artemisinin, Cinnamomum camphora alcohol, oridonin and soyasaponins. Among them, paclitaxel has been widely used in the treatment of cervical cancer and achieved an efficient therapeutic effects. Now, the anti?-cancer mechanism of terpenes is a research topic. In this review, we comprehensively discussed the progresses of anti?鄄cancer mechanisms of terpenoid substances in cervical cancer.

Key words: Terpenes, Uterine cervical neoplasms, Carcinoma, Drug therapy