国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2015, Vol. 34 ›› Issue (3): 206-208.

• 论著 • 上一篇    下一篇

长方案反复降调后雌二醇水平未达标者体外受精结局探讨

王晶，刘雨生，黄玲莉，郑圣霞   

  1. 230001 合肥，安徽医科大学附属省立医院生殖医学中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2015-05-15 发布日期:2015-05-15
  • 通讯作者: 刘雨生

Pregnancy Outcome of IVF Patients with High E2 Level after Repeated Pituitary Down-Regulation

WANG Jing，LIU Yu-sheng，HUANG Ling-li，ZHENG Sheng-xia   

  1. Reproductive Medical Center，Anhui Provincial Hospital，Anhui Medical University，Hefei 230001，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-05-15 Online:2015-05-15
  • Contact: LIU Yu-sheng

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摘要： 目的：探讨长方案体外受精（IVF）中经反复降调而雌二醇（E2）仍为高水平患者的助孕结局。方法：回顾性分析2012年1月—2014年8月于安徽医科大学附属省立医院生殖医学中心行长效长方案反复降调节E2水平难以达到降调标准的6例患者的临床资料。结果：4例患者直接行超促排卵，其中2例获得临床妊娠；1例改行微刺激方案后获得临床妊娠；1例给予来曲唑（LE）继续治疗后促排卵，获得临床妊娠。结论：反复降调后E2不达标准者仍可获得较好的IVF妊娠结局。

关键词: 垂体, 雌激素类, 生殖技术, 辅助, 排卵诱导, 妊娠结局

Abstract: Objective: To investigate the pregnancy outcome of those IVF patients with high E2 level after the repeated pituitary down-regulation with the long protocol. Methods：It is a retrospective study. Six IVF patients whose E2 levels did not match the criteria after the repeated pituitary down-regulation with long protocol were analyzed, from January 2012 to August 2014. Results：Four patients were treated with direct COH, and two patients had clinical pregnancy. One patient had clinical pregnancy after changing to the mini-stimulation protocol. One patient had clinical pregnancy after using LE and COH. Conclusions：Those IVF patients with E2 level not reaching the criteria after the repeated pituitary down-regulation could obtain ideal pregnancy outcome through regulating their protocols of induced ovulation.

Key words: Pituitary gland, Estrogens, Reproductive techniques, assisted, Ovulation induction, Pregnancy outcome