国际生殖健康/计划生育杂志 ›› 2026, Vol. 45 ›› Issue (1): 32-34.doi: 10.12280/gjszjk.20250350

• 病例报告 • 上一篇    下一篇

高龄ART受孕合并宫颈机能不全行两次紧急宫颈环扎术后足月分娩一例

刘菁, 石洁(), 高晗, 李艳丽, 孟婷竹, 程诗语   

  1. 430065 武汉科技大学医学部医学院(刘菁,孟婷竹,程诗语);华中科技大学同济医学院附属湖北妇幼保健院妇科Ⅱ(石洁,高晗,李艳丽)
  • 收稿日期:2025-07-07 出版日期:2026-01-15 发布日期:2026-02-02
  • 通讯作者: 石洁 E-mail:shijie@hbfy.com

A Case of Successful Delivery after Two Emergency Cervical Cerclages in A Woman of Advanced Age with Cervical Insufficiency Undergoing ART Conception

LIU Jing, SHI Jie(), GAO Han, LI Yan-li, MENG Ting-zhu, CHENG Shi-yu   

  1. School of Medicine, Wuhan University of Science and Technology, Wuhan 430065, China (LIU Jing, MENG Ting-zhu, CHENG Shi-yu); Department of Gynecology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China (SHI Jie, GAO Han, LI Yan-li)
  • Received:2025-07-07 Published:2026-01-15 Online:2026-02-02
  • Contact: SHI Jie E-mail:shijie@hbfy.com

摘要:

高龄辅助生殖技术(assisted reproductive technology,ART)受孕合并宫颈机能不全是导致妊娠中期流产和极早产的重要危险因素,妊娠期进行有效管理对改善妊娠结局至关重要。报告1例通过ART受孕的36岁高龄产妇,在妊娠中期因宫颈外口扩张4 cm、羊膜囊突出于宫颈外口行紧急宫颈环扎术,术后8 d羊膜囊于宫颈侧面突出,再次行紧急宫颈环扎术,并辅以抗感染、抑制宫缩、保胎等对症治疗,经综合管理,患者成功维持妊娠至足月并顺利分娩。提示对于ART助孕合并宫颈机能不全的高龄患者,若反复出现宫颈扩张、羊膜囊突出,适时实行多次紧急宫颈环扎术结合围术期管理,是实现足月妊娠的一种可行治疗方案。

关键词: 环扎术,宫颈, 宫颈功能不全, 妊娠, 生殖技术,辅助, 足月分娩

Abstract:

Advanced maternal age in conjunction with assisted reproductive technology (ART) and cervical insufficiency constitutes a significant risk factor for mid-trimester pregnancy loss and extreme preterm delivery. The effective management of this condition is crucial for improving the pregnancy outcomes. This report presents a case of an advanced maternal patient, 36-year-old, who conceived via ART. During the second trimester, the emergency cervical cerclage was performed due to the cervical incompetence manifested as cervical dilation of 4 cm with protrusion of the amniotic sac through the external cervical os. The secondary emergency cervical cerclage was performed after eight days of the first operation, due to the recurrent amniotic sac protrusion lateral to the cervical canal. The adjunctive management included anti-infective therapy, tocolysis, and fetal preservation treatment. Through comprehensive multidisciplinary management, the patient successfully maintained the pregnancy to term and achieved vaginal delivery. This successful case suggested that for those elderly patients with ART-assisted pregnancy and cervical insufficiency, if cervical dilation and amniotic sac protrusion occur repeatedly, the multiple emergency cervical cerclage combined with perioperation management is a feasible treatment option for achieving full-term pregnancies.

Key words: Cerclage, cervical, Uterine cervical incompetence, Pregnancy, Reproductive techniques, assisted, Term birth