国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2010, Vol. 29 ›› Issue (1): 15-17.

• 综述 • 上一篇    下一篇

卵巢生殖干细胞研究进展

罗雪珍综述;李大金审校

  

  1. 复旦大学附属妇产科医院
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-01-15 发布日期:2010-01-15

Research Progress in Ovarian Germline Stem Cells

LUO Xue-Zhen;LI Da-Jin   

  1. Hospital and Institute of Obstetrics and Gynecology, Fudan University Shanghai Medical College
  • Received:1900-01-01 Revised:1900-01-01 Published:2010-01-15 Online:2010-01-15

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摘要： 近来研究显示，卵巢中可能存在具有自我更新和分化潜能的生殖干细胞，尽管数量很少，但能产生新的卵母细胞和维持始基卵泡发生。对生殖干细胞的分离培养及其分化调控的研究将会加深研究者对生殖生理的认识，并为保留卵巢恶性肿瘤患者的生育功能及对卵巢性不孕症的治疗提供新的策略。

关键词: 卵巢, 生殖干细胞, 分化调控

Abstract: Recent studies have shown that ovary may contain germline stem cells which have potential of self-renewal and differentiation. Germline stem cells can produce new oocytes and maintain primordial follicles. The studies aimed at exploring the isolation and culture of germline stem cells and the regulation of the differentiation of germline stem cells may throw light in our cognition of reproductive physiology, and provide new strategy in treatment of ovarian infertility and preservation of fertility of ovarian malignant cancer patients.

Key words: Ovary, Germline stem cells, Differentiation regulation