国际生殖健康/计划生育杂志

国际生殖健康/计划生育 ›› 2013, Vol. 32 ›› Issue (6): 490-493.

• 综述 • 上一篇    下一篇

辅助生殖技术相关产科结局的研究进展

高 靓, 李 红   

  1. 215002 苏州，南京医科大学附属苏州医院生殖与遗传中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2013-11-15 发布日期:2013-11-15
  • 通讯作者: 李 红

Obstetric Outcomes of Assisted Reproductive Technology

GAO Liang，LI Hong   

  1. Center for Reproduction and Genetics，Nanjing Medical University Affiliated Suzhou Hospital，Suzhou 215002，Jiangsu Province，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2013-11-15 Online:2013-11-15
  • Contact: LI Hong

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摘要： 辅助生殖技术（assisted reproductive technology，ART）的开展解决了许多不孕夫妇的生育需求，随着ART中新技术的开展和子代人数的增加，ART的安全性引起更多关注。综述ART与多种妊娠期并发症及不良产科结局的关系，提示经ART妊娠女性发生妊娠期高血压疾病、产科出血、妊娠期糖尿病的风险升高，ART子代发生早产、低出生体质量及出生缺陷风险升高。其机制目前尚不明确，潜在的不孕背景可能是引起不良产科结局的原因之一。对于经ART妊娠妇女，应重视其围生期保健并提供必要的产前筛查及诊断以改善母婴预后。

关键词: 生殖技术, 辅助, 妊娠并发症, 妊娠结局, 先天畸形

Abstract: The assisted reproductive technology （ART） has met the demands of many infertile couples. With the development of new methods of ART and the increasing population of children conceived via ART，the safety of ART gets more and more attention. In this review，the relationship between ART and pregnancy complications, as well as diverse obstetric outcomes, was discussed. It is suggested that there were increased incidences of hypertensive disorders in pregnancy，obstetric hemorrhage, and gestational diabetes mellitus following ART. In addition，ART children had increased risks of premature，low birthweight, and birth defect. The mechanism of these obstetric outcomes related with ART have not been elucidated; however，those maternal or paternal subfertility may be an important factor. Women with ART pregnancies should get more antenatal care, and give the necessary prenatal screening and diagnosis, so as to have better maternal and perinatal outcomes.

Key words: Reproductive technology, assisted, Pregnancy complications, Pregnancy outcome, Congenital abnormalities