The Correlation between Reproductive Tract Microbiome and Chronic Endometritis

doi:10.12280/gjszjk.20220415

Abstract

Abstract:

The chronic endometritis (CE), a subtle lesion and persistent inflammation without clinical symptom or only accompanied by mild disturbances, is easily overlooked. Studies have revealed a strong link between CE and unfavorable reproductive outcomes such as infertility, recurring implant failure and recurrent abortion. Since endometrial infections are the main cause of CE, pinpointing these pathogenic microorganisms and their propensity for endometrial infection will aid in improving CE diagnosis and therapy. Microbiome can more comprehensively evaluate the endometrial microbial composition of patients with CE, which will provide more possibilities for the individualized treatment of CE in the future. Hence, this paper summarize the research progress of female reproductive tract microbiome in patients with CE, in order to provide new ideas for the diagnosis and treatment of CE.

Key words: Endometritis, Chronic disease, Microbiota, Pregnancy outcome, Therapy

ZHANG Lu, GAO Cai-hong, BAO Hong-chu. The Correlation between Reproductive Tract Microbiome and Chronic Endometritis[J]. Journal of International Reproductive Health/Family Planning, 2023, 42(2): 167-171.

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