Abstract: To inerease the efficiency of the IVF procedure by improving implantation rate and
lowering the risks of multiple gestations are the primary goals of the current assisted reproduction techology
（ART）. These aims require a much improved gamete/embryo testing and selection procedure. Though the
current approaches of microscopy-based morphology evaluation and preimplantation genetic diagnosis（PGD）
play an impartant role on it, there is lack of an objective and non-invasive techniques to detect and select
gamete/embryo at present. Since its birth in the 1990s, metabonomics has become an important part of systems
biology. Its essence is the quantitative measurement of all low molecular weight metabolites in an organism’s
cells at a specified time under specific environmental conditions. There are not many reports about

Key words: Reproductive techniques, assisted, Pregnancy, multiple, Embryo transfer, Mass spectrometry, Megnetic resonance spectrosapy