Abstract: Unexplained recurrent spontaneous abortion （哉砸杂粤）is a complex disease controlled by
various genes. The occurrence of URSA is estimted as 50% of recurrent spontaneous abortion（RSA）. 砸ecently,
many studys indicate that there are compact association between URSA and gene polymorphisms. There are
association between URSA and human leucocyte antigen （匀蕴粤）of immune system and 糟藻造枣葬糟贼燥则早藻灶藻
责燥造赠皂燥则责澡蚤泽皂泽, 蚤灶澡藻则蚤贼藻凿贼澡则燥皂遭燥责澡蚤造蚤葬糟燥则则藻造葬贼藻凿早藻灶藻责造葬泽皂蚤灶燥早藻灶葬糟贼蚤增葬贼燥则蚤灶澡蚤遭蚤贼燥则（孕粤陨原员），灾枣葬糟贼燥则，
m藻贼澡赠造藻灶藻贼藻贼则葬澡赠凿则燥枣燥造葬贼藻则藻凿怎糟贼葬泽藻（酝栽匀云砸）葬灶凿葬责燥造蚤责燥责则燥贼藻蚤灶，责则燥早藻泽贼藻则燥灶藻则藻糟藻责贼燥则（孕砸）and insulin鄄like
growth factor gene polymorphisms. It’s pathogenesis is illuminated at the gene level，which will guide clinical
prevention, therapy and prognosis. Today, the survey on URSA is becoming hot spot increasingly. This text will
overview these correlated surveys in recent years.

Key words: Abortion, habitual, Polymorphisms, single nucleotide, Immune system, Thromboembolism, Inherited thrombophilia