Abstract: PCOS， with the prevalence rate 4% to 12%， is one of the most common disorder of reproductive and endocrine systems in fertile women. The principal clinical manifestations are hyperandrogenism， irregular menstruation and infertility. The metabolic dysfunction includes insulin resistance，dyslipidemia and obesity. Those metabolic disorders are involved with the dysfunction of hypothalamic pituitary ovary axis and adrenal gland. All of these disorders may contribute to the chronic complication，such as hypertension， DM， CVD. So， doctors should closely monitoring and positively prevent those metabolic disorders.Anovulation in obese women with PCOS could be successfully treated with weight loss. Clomiphene， clomiphene plus glucocorticoid， clomiphene and estrogen?-progestin pretreatment， clomiphene and metformin，aromatase inhibitors，gonadotropin and ovarian surgery could be used for induction of ovulation in PCOS. GnRH antagonist and GnRH agonist could be used for PCOS during IVF to prevent OHSS. In vitro maturation of oocytes also is plausible.

Key words: Polycystic ovary syndrome, Ovulation induction, Ovary, Therapy