Abstract: Micronutrient deficiencies have been proved to be associated with the high reproductiverisks, such as infertility, some fetal structural defects and long-term diseases. The periconceptional period isparticularly critical stages, including fertility, conception, implantation, fetal organogenesis and placentation,which potentially affected by micronutrients. In particular，some micronutrients have antioxidant activity, sothey can effect against the oxidative damage caused by reactive oxygen species (ROS). These micronutrients protect fetus and mother in every stage of periconceptional period. So, the prophylactic use of some micronutrients may prevent adverse pregnancy outcomes. People should increase awareness of healthy diet before pregnancy. In this review, we discussed on the relationship beween some poor micronutrients and reproductive risks in the periconceptional period.

Key words: Prenatal nutrition physiology, Trace elements, Vitamins, Embryonic and fetal development, Pregnancy outcome, Reactive oxygen species