Abstract: Objective：To systematically review the application effect of two main methods in induced labor in midtrimester pregnancy of cicatricial uterus. Two methods were the Mifepristone combined with misoprostol and the mifepristone combined with ethacridine. Methods：We searched MEDLINE，EMBASE，VIP Database，Wanfang Database and CNKI（from inception to Nov. 2013）. Randomized controlled trials（RCTs） of induced labor in mid-pregnancy of cicatricial uterus, with methods of the Mifepristone combined with Misoprostol（group A） or the Mifepristone combined with Ethacridine（group B）, were reviewed and evaluated. RevMan5.2 software was used for Meta-analysis. Results：Eight literatures were included, and quality of the literatures was based on the Jadad scale scoring criteria. Meta-analysis showed that the group B was significantly superior to the group A in the time of launching uterine contraction（P＜0.000 01，WMD=-12.60，95%CI：-17.17， -8.03） and induction（P=0.000 5，WMD=-10.50，95%CI：-16.46，-4.55），placental and fetal membrane residues（Z=3.07，P=0.002，95%CI：0.37，0.80） and induced labor success rate（Z=2.31，P=0.02，95%CI：0.19，0.88），and that there were no significant differences between two groups in the total stage of labor（P=0.10，WMD=-2.16， 95%CI：-4.73，0.42） and the amount of vaginal bleeding within 24 hours after delivery（P=0.11，WMD=-29.01， 95%CI：-64.12，6.09）. Conclusions：When the induced labor in midtrimester pregnancy of cicatricial uterus was used, the Mifepristone combined with Ethacridine was significantly superior to the Mifepristone combined with Misoprostol in the time of launching uterine contraction, total time of induced labor，placental and fetal membrane residue, and the success rate of induced labor, except the total stage of labor and amount of vaginal bleeding within 24 hours after delivery.

Key words: Uterus, Cicatrix, Pregnancy trimester, second, Labor, induced, Ethacridine, Mifepristone, Misoprostol, Meta-analysis