Abstract: Objective: To analyze the levels of blood traceelements in those preschool children born from assisted reproductive technology （ＡＲＴ）, and to evaluate the developmental status, when compared with those children from natural pregnancy. Methods：Totally, 63 preschool children of ART aged 3 to 6 years （ＡＲＴ ｇｒｏｕｐ）, and 37 children of the same age and from natural pregnancy （ｃｏｎｔｒｏｌ ｇｒｏｕｐ）, from Jiangsu Province were included in this study. Those children with chromosome abnormity, overweight or obesity or other metabolic disorders, had been excluded. Levels of serum zinc, copper, ferrum, calcium, magnesium and lead were analyzed using the BH5100 and BH2100 atomic absorption spectrum instrument and meters. Results：There were not significant differences in body weight, height, bone age, serum biochemistry parameters between two groups. The mean levels of all traceelements in the ART children were in the normal ranges of the same age children. The mean level of zinc in the ART group was slightly lower, and the level of lead higher （P＜０．０1）, than those in the control group. Conclusions：The mean levels of blood traceelements in those preschool children born from ART are within the normal ranges, which suggested the ART safety in the absorption and metabolism of traceelements. It is necessary to study further in the large sample, and to track, whether the levels of zinc and lead are authentically discrepant in those ART children.

Key words: Reproductive techniques, assisted, Child, preschoo, Child development, Traceelements, Serum lead